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For Health Care Professionals

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Are you a woman or girl who lives with hemophilia A or suspects you may have it?

You’re not alone.

You deserve a diagnosis and treatment options for your hemophilia—but women with hemophilia A may not always be diagnosed. That’s why we’ve developed a Self-Advocacy Guide to help you share symptoms with your doctor and get the right treatment for you.

Download the Self-Advocacy Guide
Be embowered: you can advocate for an appropriate diagnosis and treatment

Do you feel like your doctor is not listening to you?

 48% of the women and girls who had hemophilia or were carriers who visited a Hemophilia Treatment Center (HTC) were diagnosed with hemophilia. In a real-world study of data collected from people receiving care in HTCs from 2012-2020.
48 percent icon

of the women and girls who had hemophilia or were carriers who visited a Hemophilia Treatment Center (HTC) were diagnosed with hemophilia.a

aIn a real-world study of data collected from people receiving care in HTCs from 2012-2020.

 Woman and girl icon

According to the NBDF, as many as 50% of girls and women who are carriers for hemophilia A or B have factor 8 or 9 levels are below 50% and are at risk for bleeding symptoms or heavy bleeding related to menstruation of pregnancy. All people with inherited bleeding disorders should have access to care within a Hemophilia Treatment Center or other clinical program with expertise in bleeding disorders.

If you are experiencing bleeding symptoms, it’s time for you and your doctor to talk about it.

Download Your Guide

HTC=hemophilia treatment center; MASAC=Medical and Scientific Advisory Council; NBDF=National Bleeding Disorders Foundation; WFH=World Federation of Hemophilia.

According to a healthcare provider survey:b

 42% (n=29)

felt women with inherited bleeding disorders experience less access to care as compared to men

&

 59% (n=41)

felt women experienced delays with a hemophilia diagnosis when their primary or only symptom was heavy period

bIn a 2019 survey of 70 HCPs that aimed to assess perceptions around inequities in care for patients with inherited bleeding disorders.

HTC=hemophilia treatment center; MASAC=Medical and Scientific Advisory Council; NBDF=National Bleeding Disorders Foundation; WFH=World Federation of Hemophilia.

Track Your Symptoms & Share With Your Doctor

Your symptoms matter. Nearly 2 out of 3 hemophilia “carriers” had heavy menstrual bleeding in one study— periods lasting longer than 7 days, changing pads after less than 2 hours, and/or passing blood clots larger than 1 inch or the size of a quarter. This can be linked to:

 Symptoms: Missed work & school, interruptions to social life, fatigue, mental health challenges, financial cost, poor sleep

Signs and symptoms of hemophilia in women and girls should not be dismissed. Remember, you know your body best. You can use the Self-Advocacy Guide to record any pain, swelling, and bruising you feel, which could be signs of a bleed. Bring these records with you to your doctor to help guide your conversation.

 

Start tracking: Know your symptoms to better advocate for yourself

Get your Self-Advocacy Guide
Recurring bleeds in joints can also cause long-term damage, including: chronic pain, chronic joint disease

Recurring bleeds in joints can also cause long-term damage, including:

 Chronic pain, chronic join disease icons

Signs and symptoms of hemophilia in women and girls should not be dismissed. Remember, you know your body best. You can use the Self-Advocacy Guide to record any pain, swelling, and bruising you feel, which could be signs of a bleed. Bring these records with you to your doctor to help guide your conversation.

 

Start tracking: Know your symptoms to better advocate for yourself

Get your Self-Advocacy Guide

Tammy’s Been There Too

Like many women, Tammy struggled to get the right treatment for her hemophilia. Now, she uses Esperoct® to treat her hemophilia A and is focusing on living her life on her terms.

Meet Tammy: Sharing our stories makes a difference

You deserve a diagnosis and treatment options for your hemophilia

Flexxibility Factors on your termsc

Explore 2 options for women, girls, and people assigned female at birth with hemophilia A. 

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Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] logo

Esperoct® is an extended half-life (EHL) treatment that can be used as prophylaxis or on demand.

Learn more
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Novoeight® [antihemophilic factor (recombinant)] logo

Novoeight® is a standard half-life (SHL) treatment that can be used as prophylaxis or on demand. 

Learn more

cPrior to reconstitution, Esperoct® and Novoeight® can be stored from 36 °F to 46 °F for up to 30 months, at room temperature up to 86 °F for up to 12 months, or up to 104 °F for up to 3 months. See Prescribing Information for complete product storage information.

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You’re In Charge

If you are experiencing bleeding symptoms, don't let your healthcare provider gloss over it. Provide your doctor with documentation of your symptoms. Make sure you follow up and ask questions—if something doesn’t make sense, say so. Prepare for your appointment so you can feel confident speaking up for yourself.

 

Check out more tips in your Self-Advocacy Guide!

It’s Time to Prioritize Your Health

According to WFH guidance, women, girls, and people assigned female at birth with hemophilia A should be treated the same as men and boys—but when it comes to treatment, they may not have been. That’s why we’ve developed the Self Advocacy Guide to help you talk to your doctor about your hemophilia symptoms, receive the correct diagnosis, and get the right treatment for you.

 

Learn more: These treatment options could fit your lifestyle

Explore Esperoct®
Get to know Novoeight®
Tammy with bag and yoga mat

Contact a Novo Nordisk Rare Blood Community Liaison (RBCL)

Life with a bleeding disorder can bring challenges, questions, and the occasional bump in the road. That’s why Novo Nordisk goes beyond treatment to provide information, education, and resources that might help. Our Rare Blood Community Liaisons (RBCLs) are experienced, active in the hemophilia community, and ready to provide you with one-on-one support, including:

Information about Esperoct®, Novoeight®, and trial prescriptions

Bleeding disorder and lifestyle education

Updates on local events

Tools to help you manage your bleeding disorder

Contact a Novo Nordisk Rare Blood Community Liaison (RBCL)

Life with a bleeding disorder can bring challenges, questions, and the occasional bump in the road. That’s why Novo Nordisk goes beyond treatment to provide information, education, and resources that might help. Our Rare Blood Community Liaisons (RBCLs) are experienced, active in the hemophilia community, and ready to provide you with one-on-one support, including:

Information about Esperoct®, Novoeight®, and trial prescriptions

Bleeding disorder and lifestyle education

Updates on local events

Tools to help you manage your bleeding disorder

Show more Show less

Important Safety Information

Who should not use Esperoct®?

  • You should not use Esperoct® if you are allergic to factor VIII or any of the other ingredients of Esperoct® or if you are allergic to hamster proteins

What is the most important information I need to know about Esperoct®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center
  • Call your healthcare provider right away or get emergency treatment right away if you get any signs of an allergic reaction, such as: hives, chest tightness, wheezing, dizziness, difficulty breathing, and/or swelling of the face

What should I tell my healthcare provider before using Esperoct®?

  • Before taking Esperoct®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII
  • Your body can make antibodies called “inhibitors” against Esperoct®, which may stop Esperoct® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Esperoct®

What are the possible side effects of Esperoct®?

  • Common side effects of Esperoct® include rash or itching, and swelling, pain, rash or redness at the location of infusion

Please click here for Prescribing Information.

Esperoct® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

Important Safety Information

Who should not use Novoeight®?

  • You should not use Novoeight® if you are allergic to factor VIII or any of the other ingredients of Novoeight® or if you are allergic to hamster proteins

What is the most important information I need to know about Novoeight®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia center
  • Call your healthcare provider right away and stop treatment if you get any of the following signs of an allergic reaction: rashes or hives, difficulty breathing or swallowing, tightness of the chest, swelling of the lips and tongue, Iight-headedness, dizziness or loss of consciousness, pale and cold skin, fast heartbeat, or red or swollen face or hands

What should I tell my healthcare provider before using Novoeight®?

  • Before taking Novoeight®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII
  • Your body can make antibodies called “inhibitors” against Novoeight®, which may stop Novoeight® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Novoeight® 

What are the possible side effects of Novoeight®? 

  • Common side effects of Novoeight® include inhibitors in patients who were not previously treated with factor VIII products, swelling or itching at the location of injection, and fever

Please click here for Prescribing Information.

Novoeight® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is Novoeight®?

Novoeight® (antihemophilic factor, recombinant) is an injectable medicine used to control and prevent bleeding in people with hemophilia A. Your healthcare provider may give you Novoeight when you have surgery

  • Novoeight® is not used to treat von Willebrand Disease

What is Novoeight®?

Novoeight® (antihemophilic factor, recombinant) is an injectable medicine used to control and prevent bleeding in people with hemophilia A. Your healthcare provider may give you Novoeight when you have surgery

  • Novoeight® is not used to treat von Willebrand Disease

Show more Show less
Show more Show less

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

Important Safety Information

Who should not use Esperoct®?

  • You should not use Esperoct® if you are allergic to factor VIII or any of the other ingredients of Esperoct® or if you are allergic to hamster proteins

Important Safety Information

Who should not use Esperoct®?

  • You should not use Esperoct® if you are allergic to factor VIII or any of the other ingredients of Esperoct® or if you are allergic to hamster proteins

What is the most important information I need to know about Esperoct®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center
  • Call your healthcare provider right away or get emergency treatment right away if you get any signs of an allergic reaction, such as: hives, chest tightness, wheezing, dizziness, difficulty breathing, and/or swelling of the face

What should I tell my healthcare provider before using Esperoct®?

  • Before taking Esperoct®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII
  • Your body can make antibodies called “inhibitors” against Esperoct®, which may stop Esperoct® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Esperoct®

What are the possible side effects of Esperoct®?

  • Common side effects of Esperoct® include rash or itching, and swelling, pain, rash or redness at the location of infusion

Please click here for Prescribing Information.

Esperoct® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is Novoeight®?

Novoeight® (antihemophilic factor, recombinant) is an injectable medicine used to control and prevent bleeding in people with hemophilia A. Your healthcare provider may give you Novoeight when you have surgery

  • Novoeight® is not used to treat von Willebrand Disease

What is Novoeight®?

Novoeight® (antihemophilic factor, recombinant) is an injectable medicine used to control and prevent bleeding in people with hemophilia A. Your healthcare provider may give you Novoeight when you have surgery

  • Novoeight® is not used to treat von Willebrand Disease

Important Safety Information

Who should not use Novoeight®?

  • You should not use Novoeight® if you are allergic to factor VIII or any of the other ingredients of Novoeight® or if you are allergic to hamster proteins

What is the most important information I need to know about Novoeight®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia center
  • Call your healthcare provider right away and stop treatment if you get any of the following signs of an allergic reaction: rashes or hives, difficulty breathing or swallowing, tightness of the chest, swelling of the lips and tongue, Iight-headedness, dizziness or loss of consciousness, pale and cold skin, fast heartbeat, or red or swollen face or hands

What should I tell my healthcare provider before using Novoeight®?

  • Before taking Novoeight®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII
  • Your body can make antibodies called “inhibitors” against Novoeight®, which may stop Novoeight® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Novoeight® 

What are the possible side effects of Novoeight®? 

  • Common side effects of Novoeight® include inhibitors in patients who were not previously treated with factor VIII products, swelling or itching at the location of injection, and fever

Please click here for Prescribing Information.

Novoeight® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Important Safety Information

Who should not use Novoeight®?

  • You should not use Novoeight® if you are allergic to factor VIII or any of the other ingredients of Novoeight® or if you are allergic to hamster proteins

What is the most important information I need to know about Novoeight®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia center
  • Call your healthcare provider right away and stop treatment if you get any of the following signs of an allergic reaction: rashes or hives, difficulty breathing or swallowing, tightness of the chest, swelling of the lips and tongue, Iight-headedness, dizziness or loss of consciousness, pale and cold skin, fast heartbeat, or red or swollen face or hands

What should I tell my healthcare provider before using Novoeight®?

  • Before taking Novoeight®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII
  • Your body can make antibodies called “inhibitors” against Novoeight®, which may stop Novoeight® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Novoeight® 

What are the possible side effects of Novoeight®? 

  • Common side effects of Novoeight® include inhibitors in patients who were not previously treated with factor VIII products, swelling or itching at the location of injection, and fever

Please click here for Prescribing Information.

Novoeight® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Important Safety Information

Who should not use Esperoct®?

  • You should not use Esperoct® if you are allergic to factor VIII or any of the other ingredients of Esperoct® or if you are allergic to hamster proteins

What is the most important information I need to know about Esperoct®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center
  • Call your healthcare provider right away or get emergency treatment right away if you get any signs of an allergic reaction, such as: hives, chest tightness, wheezing, dizziness, difficulty breathing, and/or swelling of the face

What should I tell my healthcare provider before using Esperoct®?

  • Before taking Esperoct®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII
  • Your body can make antibodies called “inhibitors” against Esperoct®, which may stop Esperoct® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Esperoct®

What are the possible side effects of Esperoct®?

  • Common side effects of Esperoct® include rash or itching, and swelling, pain, rash or redness at the location of infusion

Please click here for Prescribing Information.

Esperoct® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

Important Safety Information

Who should not use Novoeight®?

  • You should not use Novoeight® if you are allergic to factor VIII or any of the other ingredients of Novoeight® or if you are allergic to hamster proteins

What is the most important information I need to know about Novoeight®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia center
  • Call your healthcare provider right away and stop treatment if you get any of the following signs of an allergic reaction: rashes or hives, difficulty breathing or swallowing, tightness of the chest, swelling of the lips and tongue, Iight-headedness, dizziness or loss of consciousness, pale and cold skin, fast heartbeat, or red or swollen face or hands

What should I tell my healthcare provider before using Novoeight®?

  • Before taking Novoeight®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII
  • Your body can make antibodies called “inhibitors” against Novoeight®, which may stop Novoeight® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Novoeight® 

What are the possible side effects of Novoeight®? 

  • Common side effects of Novoeight® include inhibitors in patients who were not previously treated with factor VIII products, swelling or itching at the location of injection, and fever

Please click here for Prescribing Information.

Novoeight® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is Novoeight®?

Novoeight® (antihemophilic factor, recombinant) is an injectable medicine used to control and prevent bleeding in people with hemophilia A. Your healthcare provider may give you Novoeight when you have surgery

  • Novoeight® is not used to treat von Willebrand Disease

What is Novoeight®?

Novoeight® (antihemophilic factor, recombinant) is an injectable medicine used to control and prevent bleeding in people with hemophilia A. Your healthcare provider may give you Novoeight when you have surgery

  • Novoeight® is not used to treat von Willebrand Disease

Novo Nordisk Inc., 800 Scudders Mill Road, Plainsboro, New Jersey 08536 U.S.A.

Esperoct® and Novoeight® are registered trademarks of Novo Nordisk Health Care AG.
Novo Nordisk is a registered trademark of Novo Nordisk A/S.

© 2025 Novo Nordisk All rights reserved. US24ESP00079 March 2025

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