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Getting started–
what to know

We’ll walk you through what you need to know before your first infusion.

Esperoct® is administered by intravenous injection, either at a hemophilia treatment center, a healthcare provider’s office, or at home after you’ve received training. Do not administer Esperoct® yourself unless you have been shown how by a healthcare provider.

Esperoct® box, vial, syringe, and adapter
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NovoCare® is here to help eligible patients with information about co-pay assistance, the Novo Nordisk Patient Assistance Program (PAP), and the trial prescription program.

Call 1-844-668-6732 or visit the website for more information.

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What’s included

Vial with
Esperoct® powder

Esperoct® vial streaths

Vial
adapter

Adapter

Pre-filled
syringe with diluent

Syringe
Esperoct® vial, syringe, and adapter
  • Vial with Esperoct® powder
  • Vial adapter
  • Pre-filled syringe with diluent

Flexible dosing

Tammy has hemophilia A and uses Esperoct®

Prophylaxis dosing
Prophylaxis dosing
On-demand dosing

Adults and adolescents

50 IU/kg Every four days no dose adjustment needed

Children (<12 years)

65 IU/kg Twice weekly no dose adjustment needed

This regimen may be individually adjusted to less or more frequent dosing based on bleeding episodes

Adults and adolescents

40 IU/kg for minor to moderate bleeds
50 IU/kg for major bleeds

Children (<12 years)

65 IU/kg for minor, moderate, and major bleeds

For moderate bleeds, an additional dose may be administered after 24 hours.

For major bleeds, additional dose(s) may be administered approximately every 24 hours.

Prepare Esperoct® in 3 simple steps

Esperoct® comes with a MixPro® syringe that simplifies the reconstitution process into three quick steps.

Please note, these are not the complete Esperoct® Instructions for Use. Please see the Instructions for Use provided with the Prescribing Information.

MixPro® reconstitution video

It takes just 2 minutes to administer your Esperoct® infusion.

Infusion steps

  1. After drawing the reconstituted solution into the syringe, detach the syringe from the vial adapter by turning the syringe counterclockwise.
  2. Attach the syringe to the luer end of an infusion needle set. Do not administer Esperoct® in the same tubing or container with other medicines.
  3. Infuse the reconstituted Esperoct® intravenously slowly over about 2 minutes.

Please note, these are not the complete Esperoct® Instructions for Use. Please see the Instructions for Use provided with the Prescribing Information.

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After infusion, safely dispose of the syringe with the infusion set, the vial with the vial adapter, any unused product, and other used materials.

Set a reminder for your calendar.

Keep track of your Esperoct® infusion schedule with a reminder on your calendar.

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Looking for more resources?

We’ve gathered resources that you may find helpful.

View the resources
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Important Safety Information

Who should not use Esperoct®?

  • You should not use Esperoct® if you are allergic to factor VIII or any of the other ingredients of Esperoct® or if you are allergic to hamster proteins

What is the most important information I need to know about Esperoct®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center
  • Call your healthcare provider right away or get emergency treatment right away if you get any signs of an allergic reaction, such as: hives, chest tightness, wheezing, dizziness, difficulty breathing, and/or swelling of the face

What should I tell my healthcare provider before using Esperoct®?

  • Before taking Esperoct®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII
  • Your body can make antibodies called “inhibitors” against Esperoct®, which may stop Esperoct® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Esperoct®

What are the possible side effects of Esperoct®?

  • Common side effects of Esperoct® include rash or itching, and swelling, pain, rash or redness at the location of infusion

Please click here for Prescribing Information.

Esperoct® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

Show more Show less
Show more Show less

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

Important Safety Information

Who should not use Esperoct®?

  • You should not use Esperoct® if you are allergic to factor VIII or any of the other ingredients of Esperoct® or if you are allergic to hamster proteins

Important Safety Information

Who should not use Esperoct®?

  • You should not use Esperoct® if you are allergic to factor VIII or any of the other ingredients of Esperoct® or if you are allergic to hamster proteins

What is the most important information I need to know about Esperoct®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center
  • Call your healthcare provider right away or get emergency treatment right away if you get any signs of an allergic reaction, such as: hives, chest tightness, wheezing, dizziness, difficulty breathing, and/or swelling of the face

What should I tell my healthcare provider before using Esperoct®?

  • Before taking Esperoct®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII
  • Your body can make antibodies called “inhibitors” against Esperoct®, which may stop Esperoct® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Esperoct®

What are the possible side effects of Esperoct®?

  • Common side effects of Esperoct® include rash or itching, and swelling, pain, rash or redness at the location of infusion

Please click here for Prescribing Information.

Esperoct® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Important Safety Information

Who should not use Esperoct®?

  • You should not use Esperoct® if you are allergic to factor VIII or any of the other ingredients of Esperoct® or if you are allergic to hamster proteins

What is the most important information I need to know about Esperoct®?

  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center
  • Call your healthcare provider right away or get emergency treatment right away if you get any signs of an allergic reaction, such as: hives, chest tightness, wheezing, dizziness, difficulty breathing, and/or swelling of the face

What should I tell my healthcare provider before using Esperoct®?

  • Before taking Esperoct®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII
  • Your body can make antibodies called “inhibitors” against Esperoct®, which may stop Esperoct® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Esperoct®

What are the possible side effects of Esperoct®?

  • Common side effects of Esperoct® include rash or itching, and swelling, pain, rash or redness at the location of infusion

Please click here for Prescribing Information.

Esperoct® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

What is Esperoct®?

Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery

  • Esperoct® is not used to treat von Willebrand Disease

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